近年来,在国外的有机化学教材中,已广泛介绍“有机不对称合成”的内容。国内新出的一些教材上也开始增加这方面的材料。本文就有关这方面的某些问题,提出一点粗浅的看法供讨论。(一)定义:有机不对称合成又称有机手征性合成。凡含有潜手征件中心的分子,在手征性试剂、催化剂或反应环境,以及一些不对称物理因素如园偏振光的作用下,发生具有对映体区别反应,产生一对对映体中的一个占优势的结果。此外,如分子中同时含有手性及潜手性中心,在与非手性试剂或反应物反应时,原分子 In recent years, foreign organic chemistry textbooks, has been widely introduced “organic asymmetric synthesis” content. Some new materials in the country have also begun to increase this material. This article on some issues in this area, put forward some superficial views for discussion. (A) Definition: Organic asymmetric synthesis, also known as organic chiral synthesis. Where molecules containing latent sign centers, with chiral reagents, catalysts or reaction environment, and some asymmetric physical factors such as the role of circular polarized light, the occurrence of enantiomerically distinct reaction, resulting in a pair of enantiomers A dominant result. In addition, if a molecule contains both chiral and sub-chiral centers, upon reaction with a non-chiral reagent or reactant, the original molecule