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对140 例感染性疾病用乳酸左氧氟沙星治疗,每次静脉滴注100～200m g,每日2 次,疗程5～10d,观察其疗效及不良反应发生率。结果显示140 例中痊愈107 例(76.4% ),有效26 例(18.6% ),总有效率95% 。细菌培养阳性32 例,转阴率100% 。140 例中肠道感染72 例,总有效率98% ;泌尿系感染23 例,总有效率93.5% ;呼吸道感染38 例,总有效率92.4% ;皮肤及其它感染7 例,总有效率91% 。140 例患者不良反应发生率为5% ,均不影响治疗。因此,乳酸左氧氟沙星用于细菌性感染既安全又高效,可广泛用于临床。
140 cases of infectious diseases with levofloxacin lactate treatment, each intravenous drip 100 ~ 200m g, 2 times a day for 5 ~ 10d, the efficacy and adverse reactions were observed. Results showed that in 140 cases, 107 cases (76.4%) were cured, 26 cases (18.6%) were effective and the total effective rate was 95%. Bacterial culture positive in 32 cases, the negative rate of 100%. 140 cases of midgut infection in 72 cases, the total efficiency of 98%; urinary tract infection in 23 cases, the total effective rate 93.5%; respiratory tract infection in 38 cases, the total effective rate was 92.4%; skin and other infections in 7 cases, the total effective rate was 91% . The incidence of adverse reactions in 140 patients was 5%, did not affect the treatment. Therefore, levofloxacin lactate for bacterial infection is safe and efficient, can be widely used in clinical.