论文部分内容阅读
目的探讨急性心肌梗死患者行冠脉介入术(PCI)后无/慢复流现象发生与炎症的关系。方法前瞻性研究656例急性心肌梗死行PCI的患者,其中632例患者随访至一年,60例发生PCI术后无/慢复流现象为复流不良组;从其余的572例患者中,用Excel随机函数表随机抽取120例患者设为对照组,为避免统计学偏差。结果复流不良组炎症指标,如白细胞总数、中性粒细胞总数、高敏C反应蛋白,以及死亡率、心脏不良事件、糖尿病及胰岛素水平均高于对照组(P<0.05或P<0.01);复流不良患者左室射血分数减低、左室舒张末期内径增大(P<0.01)。结论炎症反应与急性心肌梗死患者PCI术后无/慢复流现象的发生有关,并严重影响患者的预后。
Objective To investigate the relationship between no / slow reflow phenomenon and inflammation after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction. Methods A total of 656 patients with acute myocardial infarction who underwent PCI were prospectively studied. Among them, 632 patients were followed up for one year, and 60 patients who had no / slow reflow after PCI had poor recovery. From the remaining 572 patients, Excel random function table randomly selected 120 patients as a control group, in order to avoid statistical bias. Results The indexes of inflammation in poor recovery group such as total number of leukocytes, total number of neutrophils, high sensitive C - reactive protein, mortality, cardiac adverse events, diabetes mellitus and insulin were higher than those in control group (P <0.05 or P <0.01). Left ventricular ejection fraction decreased, and left ventricular end-diastolic diameter increased in patients with poor reflow (P <0.01). Conclusion The inflammatory reaction is related to the occurrence of no / slow reflow after PCI in patients with acute myocardial infarction, and seriously affects the prognosis of patients.