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用三种方法（饮水加氟、四氧嘧啶肌注、四氧嘧啶肌注和饮水加氟）处理Ｗｉｓｔａｒ大鼠，发现氟化物对糖尿病大鼠的毒性比较显著。
Wistar rats were treated with three methods (drinking water plus fluoride, alloxan intramuscular injection, alloxan intramuscular injection and drinking water plus fluoride), and the toxicity of fluoride on diabetic rats was found to be significant.