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碘杂环64号(IHC-64)化学名为3,6一二[二甲氨基]一二苯骈碘杂环甲酸盐。它是兰州大学化学系黄文魁合成的一种新型化合物。文献报道该化合物有降血压[1]和抗心律失常作用[2]。经临床初步观察IHC-64尚有降低血清胆固醇作用[3],但至今动物实验资料国内外未见报道,为此我们开展了IHC-64对小鼠血清胆固醇和甘油三酯影响的研究.
Iodocycline No. 64 (IHC-64) has a chemical name of 3,6-bis[dimethylamino]-diphenylsulfonium iodocyclocarboxylate. It is a novel compound synthesized by Huang Wenkui, a chemical department of Lanzhou University. It has been reported in the literature that this compound has anti-hypertension [1] and anti-arrhythmic effects [2]. The preliminary clinical observation of IHC-64 has a role in lowering serum cholesterol [3], but there have been no reports of animal experimental data at home and abroad. For this reason, we conducted a study on the effect of IHC-64 on serum cholesterol and triglyceride in mice.