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作者用导升明(doxium,calciumdobesilute)治疗单纯型糖尿病视网膜病变患者32例,设对照组26例患者不用导升明,经治疗3月,观察治疗前后的血液流变学和眼底变化。结果表明,治疗组患者的全血粘度、血浆粘度、红细胞电泳时间和纤维蛋白原均比服药前降低(P<0.05),而对照组无明显变化(P>0.05)。治疗组眼底病变趋于稳定和改善者多于对照组(P<0.05),提示导升明能降低糖尿病患者的血液粘度,改善和稳定其眼底病变。
The authors used doxium (calciumdobesilute) in the treatment of simple diabetic retinopathy in 32 patients, the control group, 26 patients without escalation, after treatment for 3 months, observed before and after treatment of hemorheology and fundus changes. The results showed that the whole blood viscosity, plasma viscosity, erythrocyte electrophoresis time and fibrinogen in treatment group were lower than those before treatment (P <0.05), but there was no significant change in control group (P> 0.05). The fundus lesions in the treatment group tended to be stable and improved more than those in the control group (P <0.05), which indicated that Dijumingming can reduce the blood viscosity of diabetic patients and improve and stabilize the fundus lesions.