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目的:观察参赭培气汤联合FOLFOX6方案化疗对晚期肝癌患者免疫功能及生活质量的影响。方法:将符合纳入标准的80例晚期肝癌患者随机分为治疗组和对照组各40例,对照组行FOLFOX6方案化疗治疗,治疗组行参赭培气汤+FOLFOX6方案化疗治疗,比较两组临床疗效、免疫功能改善及生活质量评分情况。结果:治疗组临床总有效率高于对照组,且生活质量评分也高于对照组(P<0.05);两组治疗后免疫功能指标较治疗前不同程度改善,但是治疗组改善幅度更大(P<0.05或P<0.01)。结论:参赭培气汤联合FOLFOX6方案化疗治疗晚期肝癌有一定的疗效,能改善患者免疫功能,提高其生活质量。
Objective: To observe the effects of Shenzao Peiqi Decoction combined with FOLFOX6 regimen on immune function and quality of life in patients with advanced liver cancer. Methods: Eighty patients with advanced HCC who met the inclusion criteria were randomly divided into treatment group (40 cases) and control group (40 cases). The control group was treated with FOLFOX6 regimen. The treatment group was treated with Hypobritus soup plus FOLFOX6 regimen. Efficacy, improved immune function and quality of life scores. Results: The total clinical effective rate in the treatment group was higher than that in the control group, and the quality of life score was also higher than that in the control group (P <0.05). The immune function of the two groups improved to some extent after treatment, but the treatment group improved more P <0.05 or P <0.01). Conclusion: Shenzhong Peiqi Decoction combined with FOLFOX6 regimen in the treatment of advanced liver cancer has certain curative effect, which can improve patients’ immune function and improve their quality of life.