目的探讨运用综合干预方法治疗儿童孤独症的疗效。方法 30例儿童孤独症患儿采用综合干预方法,治疗前及治疗半年后采用心理教育量表(PEP)、儿童孤独症评定量表(CARS)评估治疗效果。结果综合治疗能提高PEP各项目得分,除模仿、表达外,差异均有显著性;CARS评分降低,差异有显著性。结论综合干预措施能提高孤独症患儿的能力,降低功能障碍。 Objective To explore the use of comprehensive intervention in the treatment of children with autism. Methods Thirty children with autism were enrolled in this study. The interventions were performed before and after six months of treatment. Psychological education scale (PEP) and autism assessment scale (CARS) were used to evaluate the therapeutic effect. Results Comprehensive treatment can improve the PEP score, except for imitation, expression differences were significant; CARS score decreased, the difference was significant. Conclusion Comprehensive interventions can improve the ability of children with autism and reduce dysfunction.