单次剂量抗生素治疗妊娠期无症状菌尿

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鉴于约30%未经治疗的妊娠期无症状菌尿患者在孕期将发展为急性肾盂肾炎,故大多数作者认为对无症状菌尿应予治疗.作者对50例无症状菌尿孕妇予单次剂量抗生素治疗获满意效果.方法对首次产前检查的孕妇常规行清洁中段尿培养,其中50例连续2次培养的同种菌落数>10万/ml,确诊为无症状菌尿.按药物敏感试验选用氨苄青霉素3克或头孢氨苄2克,一次口服,并于服药后1、2、4、8周随访.8周期间尿培养阴性者为治愈,2周内出现同种细菌感染者为复发,出现不同细菌或2周后发现同种细菌者为再感染.50例患者的病原菌大多为大肠杆菌(52%),其中仅38%对氨苄青霉素敏感,而全部病原菌中98%对头孢氨苄敏感.结果单剂量抗生素的治愈率为84% About 30% of untreated asymptomatic asymptomatic patients with gestosis during pregnancy will develop acute pyelonephritis, so most authors believe that asymptomatic bacteriuria should be treated. The authors of 50 cases of asymptomatic bacteriuria in pregnant women to a single Dose antibiotic therapy was satisfactory.Methods The first prenatal examination of pregnant women routinely clean urine culture, of which 50 cases of two consecutive cultures of the same number of colonies> 100,000 / ml, diagnosed as asymptomatic bacteriuria.According to drug-sensitive The test selected ampicillin 3 grams or 2 grams of cephalexin once orally and at 1,2,4,8 weeks after taking the drug were followed up during the 8-week negative urine culture was cured within 2 weeks of the same type of bacterial infection were relapse Of the total bacterial pathogens were found to be re-infected after emergence of different bacteria or after 2 weeks.50 of them were mostly E. coli (52%), of which only 38% were sensitive to ampicillin and 98% of all pathogens were sensitive to cephalexin Results The cure rate of single-dose antibiotics was 84%
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