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本文采用双抗体夹心酶免疫测定法测定了 85例皮疹伴发热患儿及对照组 80例无皮疹发热上感患儿尿液的视黄醇结合蛋白 (Retinolbindingprotein ,RBP)含量 ,皮疹组患儿尿RBP含量全部高于正常值 ,而对照组患儿尿RBP含量全部在正常范围内 ,二组间经t检验 ,P <0 0 1,有显著性意义。因为尿RBP是早期肾功能损害最敏感而可靠的检测指标 ,所以本资料结果提示皮疹患儿可能有肾损伤
In this paper, we measured the content of retinol-binding protein (RBP) in urine of 85 children with rash fever and 80 children with fever without rash using double antibody sandwich enzyme immunoassay, RBP content were all higher than the normal value, while the control group of children with urinary RBP content all within the normal range, t test between the two groups, P <0 01, a significant significance. Because urine RBP is the most sensitive and reliable indicator of early renal impairment, this data suggests that children with rash may have kidney damage