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多胺是一类具有两个以上氨基的脂肪族化合物,它们在生物体内含量的动态平衡受合成、转运、降解及互换等过程的影响,多胺及其合成和转运系统与病原菌的致病性相关。本文综述了多胺在细菌毒力因子的转录和翻译、细菌生物膜的合成、细菌对抗生素的抗性、细菌对抗宿主的酸性胁迫和氧化胁迫、细菌对抗宿主的先天免疫防御机制、细菌致病性生物分子的合成等方面的重要作用。
Polyamines are a class of aliphatic compounds with two or more amino groups. The dynamic balance of their contents in the organism is affected by the process of synthesis, transport, degradation and exchange. Polyamines, their synthesis and transport systems, and pathogenic pathogens Sex related. This review summarizes the mechanisms involved in the transcription and translation of bacterial virulence factors, the synthesis of bacterial biofilms, the resistance of bacteria to antibiotics, the acid and oxidative stress of bacteria against the host, the innate immune defense mechanism of the bacteria against the host, Sexual biomolecular synthesis and other aspects of the important role.