论文部分内容阅读
目的探讨放化疗综合治疗中晚期鼻咽癌的临床疗效。方法 100例中晚期鼻咽癌患者随机分为单纯放疗组和放化疗综合治疗组,各50例,采用常规放疗,放化疗综合治疗组采用放化疗综合疗法。结果单纯放疗组局部控制率(54.3%)和5年生存率(28.1%)均比放化疗综合治疗组(78.5%、64.5%)低,单纯放疗组的远处转移率(68.7%)比放化疗综合治疗组(22.5%)高。两者之间比较差异有统计学意义(P<0.05);两组毒性反应差异无统计学意义(P>0.05),经过对症治疗后均能治愈。结论放化疗联合治疗中晚期鼻咽癌可以提高局部控制率、5年生存率,降低远处转移率,疗效确切,降低毒副作用,具有较高临床推广价值。
Objective To investigate the clinical effects of radiotherapy and chemotherapy on advanced nasopharyngeal carcinoma. Methods 100 patients with advanced nasopharyngeal carcinoma were randomly divided into radiotherapy and radiotherapy alone group and radiotherapy and chemotherapy group, 50 cases in each group. The patients in radiotherapy and chemotherapy combined radiotherapy and chemotherapy group were treated with radiotherapy and chemotherapy. Results The local control rate (54.3%) and 5-year survival rate (28.1%) in radiotherapy group were lower than that in radiotherapy and chemotherapy group (78.5%, 64.5%), while the radiotherapy group Chemotherapy combined treatment group (22.5%) high. The difference between the two groups was statistically significant (P <0.05). There was no significant difference in toxicity between the two groups (P> 0.05). After symptomatic treatment, all the patients were cured. Conclusions Radiotherapy combined with chemotherapy for advanced nasopharyngeal carcinoma can improve the local control rate, 5-year survival rate, reduce the distant metastasis rate, and has the exact curative effect and reduces the side effects. It has a high clinical value of popularization.