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中毒性休克综合症(TSS)可以发生在带有金黄色葡萄球菌感染灶的患者,但本病大部分见于行经期的妇女,并且证明长期使用阴道软塞是该病发生的重要因素。虽然阴道软塞引起中毒性休克综合症的确切机理尚未清楚,但阴道软塞作为本病的病因已被近来一些观察资料阐述。有报导23例中毒性休克综合症患者在治疗前的宫颈阴道分泌物培养,其中17例(73.9%)有凝固酶阳性的金黄色葡萄球菌菌落生长,未行经的为0—11%,停经妇女为7%;另有报导,38个患者的宫颈或阴道分泌物中有11例分离出细菌,其中8例被Ⅰ簇噬菌体溶解,有7例被29簇噬菌体溶解,并提示这种细菌可能是特殊的凝固酶阳性的金黄色葡萄球菌簇。
Toxic shock syndrome (TSS) can occur in patients with Staphylococcus aureus foci, but most of the disease is seen in women during menstruation and demonstrates that long-term use of vaginal soft plug is an important factor in the disease. Although the exact mechanism of vaginal soft plug induced toxic shock syndrome is not yet clear, but as the cause of this disease, vaginal soft plug has been described by some recent observations. Twenty-three patients (73.9%) with coagulase-positive Staphylococcus aureus colonies grew in 0 to 11% of unacceptable women with menopausal women who reported 23 patients with toxic shock syndrome before treatment for cervical vaginal secretions Was 7%. In addition, 11 of 38 patients with cervical or vaginal secretions were reported to have isolated bacteria, of which 8 were lysed by Group I phage and 7 were lysed by 29 cluster phage and suggested that this bacterium may be Coagulase-positive Staphylococcus aureus cluster.