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目的:旨在了解不同血液净化方式对尿毒症患者生存质量影响。方法:选择血液透析治疗1～4年的维持性血液透析患者90例,随机分配至血液透析组、血液透析滤过组、高通量血液透析组,每组30例;所有患者均每周治疗3次,每次4小时;观察时间6个月;利用SF-36量表调查不同透析方式对患者生理机能(PF)、生理职能(RP)、躯体疼痛(BP)、一般健康状况(GH)、精力(V1)、社会功能(SF)、情感职能(RE)、精神健康(MH)、健康变化(HT)方面的影响,评价不同血液净化方式后患者生存质量的变化。结果;不同血液净化方式治疗后3组患者SF-36量表PF、RP、BP、GH、RE、MH六项评分的组间差异均有统计学意义(P<0.05)。结论:高通量血液透析组在提高治疗效果、降低并发症发病率和改善患者生存质量方面的作用要优于血液透析滤过组和血液透析组。
Objective: To understand the impact of different blood purification methods on the quality of life of uremic patients. Methods: 90 hemodialysis patients who were treated with hemodialysis for 1 to 4 years were randomly assigned to hemodialysis group, hemodiafiltration group and high-flux hemodialysis group, 30 cases in each group. All patients were treated weekly 3 times, 4 hours each time; the observation time was 6 months; SF-36 scale was used to investigate the effects of different dialysis methods on the patients’ physical function (PF), physical function (RP), somatic pain (BP), general health (GH) (V1), social function (SF), emotional function (RE), mental health (MH), health change (HT), and evaluate the quality of life of patients after different blood purification methods. Results The differences of SF-36 SF-36 scores among the three groups after treatment with different blood purification methods were statistically significant (P <0.05). Conclusion: The high-throughput hemodialysis group is better than hemodiafiltration group and hemodialysis group in improving the therapeutic effect, reducing the incidence of complications and improving the quality of life of patients.