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天疱疮是一种自身免疫性的、发疱性的粘膜皮肤疾病。它虽有多种类型,但以寻常性天疱疮(PPV)最为多见。据统计,约有70％的PPV患者口腔为其初发损害区;约90％的患者在发病过程中出现口腔损害,甚至有50％的患者终身只累及口腔。然而,口腔科领域的书籍对该疾病的治疗描述甚少,因而,临床医师在偶遇类似病例时,常感棘手。 一、历史回顾 大疱疮临床虽然少见,但多较严重。在50年代Thorn等人将肾上腺皮质激素(下称激素)用于治疗大疱疮之前,主要采用砷
Pemphigus is an autoimmune, blistering mucocutaneous disease. Although it has many types, it is most common with pemphigus vulgaris (PPV). According to statistics, about 70% of patients with PPV oral lesions for the initial area; about 90% of patients with oral lesions during the onset, and even 50% of patients lifetime involvement only the mouth. However, books in the field of dentistry have described very little about the treatment of the disease, and as a result clinicians often find it tricky to encounter similar cases. First, the historical review Although the clinical pemphis rare, but more serious. Thorn and others in the 50’s adrenal cortex hormone (hereinafter referred to as hormone) for the treatment of bullous sores, the main use of arsenic