目的系统研究广西39年来霍乱流行与地理位置及地形地貌的关系。方法应用卫生统计学和地理流行病学方法。结果广西霍乱发病主要集中在沿海地区3个市 ,沿海地区发病率明显高于内陆地区 ;内陆地区1990～1999年发病率高于1961～1989年 ,沿海则相反 ;主要地貌类型中以沿海发病率为最高 ,但1990～1999年山区发病率高于1961～1989年 ,仅次于沿海地区 ;海拔高度以小于50米的县市发病率最高 ,与1961～1989年不同的是 ,1990～1999年除小于50米的县市外 ,随着海拔高度的增加 ,累计发病率越高 ;发病县市中边界县市所占的比例高 ,且累计发病率等级高 ;累计发病率等级分布图显示周高、中低和南北高、东西低的特点 Objective To study the relationship between cholera epidemic and geographical location and topography in Guangxi during the past 39 years. Methods Applying health statistics and geo-epidemiological methods. Results The incidence of cholera in Guangxi was mainly concentrated in three cities along the coast and the incidence in the coastal areas was significantly higher than that in the inland areas. The incidence rate of inland areas from 1990 to 1999 was higher than that from 1961 to 1989, while that in the coastal areas was opposite. In the main types of geography, The incidence was the highest, but the incidence was higher in mountainous area from 1990 to 1999 than in 1961 ~ 1989, second only to the coastal areas; the highest incidence was less than 50 meters in the counties and cities, with the difference from 1961 ~ 1989, With the exception of counties and cities less than 50 meters in 1999, the cumulative incidence increased with the altitude above sea level; the proportion of border counties and cities in the affected counties and cities was high, and the cumulative incidence rate was high; the cumulative incidence rating distribution Show week high, low and north-south high, east-west features