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目的:实验研究盆炎清灌肠剂的抗炎、活血化瘀作用。方法:采用二甲苯致小鼠耳肿、冰醋酸致小鼠腹腔毛细血管通透性、大鼠棉球肉芽肿炎症模型;肾上腺素引起大鼠血微循环障碍造成血瘀模型。结果:实验表明盆炎清灌肠剂对二甲苯、冰醋酸所致急性炎症有明显抑制作用,能降低小鼠腹腔毛细血管通透性;抑制棉球肉芽肿增生;明显改善血瘀模型大鼠的血液流变性。结论:盆炎清灌肠剂具有明显的抗炎和活血化瘀作用。
OBJECTIVE: To study the anti-inflammatory, blood-activating and blood-stasis effect of Pengyi Qing enema. Methods: Xylene-induced mouse ear swelling, glacial acetic acid induced peritoneal capillary permeability and rat granulomatous inflammation model; epinephrine-induced blood microcirculation disorder caused by blood stasis model. Results: The experiment showed that Penyanqing enema significantly inhibited the acute inflammation induced by xylene and glacial acetic acid, reduced peritoneal capillary permeability, inhibited the proliferation of granuloma of cotton ball, and significantly improved the blood stasis model rats Hemorheology. Conclusion: Shen Yan Qing enema enema has obvious anti-inflammatory and blood circulation.