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目的对比Jailed导丝技术与边支血管主动球囊保护技术在冠状动脉分叉病变介入治疗中的临床效果。方法选取2014年1月至2015年3月期间166例冠状动脉分叉病变行经皮冠状动脉介入(PCI)的患者,随机分为2组(Jailed导丝组82例,主动球囊保护组84例),比较两组患者的对比剂用量、手术时间、PCI术后即刻影像学效果及30天主要不良心血管事件(MACE)发生率等方面差异。结果主动球囊保护组较Jailed导丝组患者术后的TIMI 3级血流率(96%vs 85%,P<0.05)、术后30天MACE发生率(5.95%vs15.9%,P<0.05)明显降低,而对比剂用量[(59.20±10.36)ml vs(61.92±9.36)ml),P>0.05]、手术时间[(34.12±8.94)min vs(31.63±8.81)min,P>0.05]无明显增加。结论采用边支血管主动球囊保护技术提高了分叉病变PCI的临床效果,而且不增加手术时间及对比剂用量。
Objective To compare the clinical effect of Jailed guidewire technique and the technique of active grafts for lateral branch artery grafting in the treatment of coronary bifurcation lesions. Methods One hundred and sixteen patients with coronary artery bifurcation undergoing percutaneous coronary intervention (PCI) from January 2014 to March 2015 were randomly divided into 2 groups (82 in Jailed guidewire group, 84 in active balloon protection group ). The differences of contrast medium dosage, operation time, immediate imaging effect after PCI and incidence of major adverse cardiovascular event (MACE) on 30 days were compared between the two groups. Results The TIMI grade 3 blood flow rate (96% vs 85%, P <0.05) and the MACE incidence at 30 days after active balloon therapy (5.95% vs 15.9%, P < (P> 0.05), and the amount of contrast agent [(59.20 ± 10.36) ml vs (61.92 ± 9.36) ml, P> 0.05) ] No significant increase. Conclusion The technique of active balloon protection of the branch of the blood vessels improves the clinical effect of bifurcation PCI without increasing the operation time and dosage of contrast medium.