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背景:临床实际中,发现以醒脑开窍并益气养阴为治则,标本兼治可明显改善脑梗死急性期患者的神经功能恢复情况。目的:观察醒脑静注射液与安宫牛黄丸对脑梗死急性期患者神经功能障碍的影响。设计:以患者为观察对象,随机对照。单位:中国人民武装警察部队广东总队医院。对象:研究对象为武警广东总队医院神经内科1998-09/2003-09住院的脑梗死患者。方法:将脑梗死急性期患者120例随机分为醒脑静注射液组和安宫牛黄丸组及丹参粉组,各40例,治疗14d后分别观察患者的疗效、神经功能改善情况。主要观察指标:各组患者神经功能改善情况比较。结果:醒脑静注射液组、安宫牛黄丸组、丹参粉组总有效率分别为95%90%,65%,醒脑静注射液组、安宫牛黄丸组肢体瘫痪的恢复明显优于对照组,醒脑静注射液组疗效显著。结论:醒脑静注射液与安宫牛黄丸对脑梗死急性期有较好的治疗作用而且前者对神经功能缺损的恢复效果更为明显。
Background: In clinical practice, it has been found that the treatment of acute cerebral infarction can improve the recovery of nerve function in patients with cerebral infarction. Objective: To observe the effect of Xingnaojing Injection and Angong Niuhuang Wan on neurological dysfunction in patients with acute cerebral infarction. Design: Patient observation, randomized control. Unit: Chinese People’s Armed Police Corps Guangdong Corps Hospital. PARTICIPANTS: The subjects of the study were patients hospitalized with cerebral infarction in the Armed Police Corps Hospital of Guangdong Province from September 1998 to September 2003. Methods: 120 cases of acute cerebral infarction were randomly divided into Xingnaojing injection group and Angong Niuhuangwan group and Danshen powder group, 40 cases each. After 14 days of treatment, the curative effect and neurological function were observed respectively. MAIN OUTCOME MEASURES: Comparison of neurological improvement in each group. Results: The total effective rate of Xingnaojing injection group, Angong Niuhuangwan group and Danshen powder group were 95%, 90% and 65% respectively. The recovery of limb paralysis in Xingnaojing injection group and Angong Niuhuang bolus group was obviously better than The control group, Xingnaojing injection group had a significant effect. Conclusion: Xingnaojing Injection and Angong Niuhuang Wan have a better therapeutic effect on acute cerebral infarction, and the former is more effective in recovering neurological deficits.