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目的观察西咪替丁联合炎琥宁治疗小儿轮状病毒性肠炎的疗效。方法选取2011年5月—2013年5月于天等县妇幼保健院接受治疗的轮状病毒性肠炎患儿120例,按随机数字表法分为对照组和治疗组,每组60例。对照组患儿给予合理饮食、适量补液,纠正电解质紊乱和酸碱失衡以及炎琥宁注射液抗病毒等治疗,治疗组在对照组基础上给予西咪替丁治疗,比较两组患儿的临床疗效、止泻时间、脱水纠正时间、治愈时间与总疗程等。结果治疗组患儿的总有效率为96.6%,高于对照组的71.7%,差异有统计学意义(P<0.05)。治疗组的止泻时间、脱水纠正时间、治愈时间与总疗程短于对照组,差异有统计学意义(P<0.05)。结论西咪替丁联合炎琥宁治疗小儿轮状病毒性肠炎具有良好的效果,可尽早消除各项临床症状,促进患儿早日康复。
Objective To observe the effect of cimetidine combined with metronidazole in the treatment of infantile rotavirus enteritis. Methods From May 2011 to May 2013, 120 children with rotavirus enteritis treated in Tianqian MCH were randomly divided into control group and treatment group with 60 cases in each group. The control group of children given a reasonable diet, appropriate rehydration, electrolyte imbalance and correction of acid-base imbalance and antiviral therapy such as Yan Huaning injection, the treatment group was given cimetidine treatment on the basis of the control group, the two groups of children clinical Efficacy, antidiarrheal time, dehydration correction time, cure time and the total course of treatment. Results The total effective rate of the treatment group was 96.6%, which was higher than 71.7% of the control group, the difference was statistically significant (P <0.05). The antidiarrheal time, dehydration correction time, cure time and total duration of treatment in the treatment group were shorter than those in the control group, with significant difference (P <0.05). Conclusion Cimetidine combined with Yan Hu Ning rotavirus enteritis has a good effect, as soon as possible to eliminate the clinical symptoms and promote early recovery of children.