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目的了解嗜肺军团菌感染临床特点,提高对嗜肺军团菌感染的认识。方法对本院2009年9月至2010年5月诊断的88例嗜肺军团菌感染患儿的临床资料进行回顾性分析。结果 88例均存在不同程度的呼吸道感染;呼吸道以外损害:腹泻11例,湿疹3例,中性粒细胞减少6例,心肌损害8例,代谢性酸中毒3例,过敏性紫癜、鹅口疮、中耳炎、多发性肌炎、贫血各1例。其他病原体感染:合并肺炎支原体感染35例,流感病毒A7例,流感病毒B10例,副流感病毒11例,轮状病毒感染3例,呼吸道合胞病毒感染3例,腺病毒感染5例;合并2种及以上病原体感染52例,占59.09%。结论嗜肺军团菌感染以呼吸道感染为主,同时可以引起全身多系统损害以及存在多种呼吸道病原体同时感染。婴幼儿发病率较高。大环内酯类药物治疗有效,疗程7～10d。
Objective To understand the clinical characteristics of Legionella pneumophila infection and to raise awareness of Legionella pneumophila infection. Methods The clinical data of 88 children with Legionella pneumophila diagnosed in our hospital from September 2009 to May 2010 were analyzed retrospectively. Results There were different levels of respiratory infections in 88 cases. Other than respiratory tract, there were 11 cases of diarrhea, 3 cases of eczema, 6 cases of neutropenia, 8 cases of myocardial damage, 3 cases of metabolic acidosis, 3 cases of allergic purpura, thrush, Otitis media, polymyositis, anemia in 1 case. Other pathogens infection: Mycoplasma pneumoniae infection in 35 cases, influenza A7 cases, influenza B10 cases, parainfluenza virus in 11 cases, rotavirus infection in 3 cases, respiratory syncytial virus infection in 3 cases, adenovirus infection in 5 cases; merger 2 52 kinds of pathogens and above infection, accounting for 59.09%. Conclusions Legionella pneumophila infection is mainly respiratory tract infection, meanwhile it can cause systemic multiple system damage and simultaneous infection of multiple respiratory pathogens. The incidence of infants and young children is higher. Macrolide treatment effective, course of treatment 7 ~ 10d.