大气污染对大鼠细胞因子的影响

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目的分析大气污染对大鼠细胞因子的影响,以揭示大气污染对呼吸系统损害及机体影响的机制,为预防和治疗大气污染对健康的损害提供依据.方法将体重在180~220g的大鼠随机分为4组,即对照组、低剂量组、中剂量组、高剂量组,分别进行颗粒物和SO2、NO2染毒,颗粒物染毒采用气管注入法,各注入颗粒物7.5,15,30mg,灌注体积为1ml,对照组注入同体积的生理盐水.染尘后的第2d,再进行SO2和NO2混合气体染毒,低、中、高剂量组的SO2和NO2的浓度分别为8,5mg/m3;16,10mg/m3;32,20mg/m
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