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目的 研究神经生长因子 (NGF)和神经生长抑制因子 (NGI)对鸡胚背根神经节 (DRG)轴突生长的影响。方法 分离培养鸡胚 DRG,加入 NGF、NGI并观察它们对轴突生长的影响。结果 DRG轴突在含 NGF的培养液中迅速生长 ,加入 NGI后这种生长被抑制。结论 NGF可促进 DRG轴突的生长 ,而 NGI抑制它的生长。
Objective To investigate the effects of nerve growth factor (NGF) and nerve growth inhibitory factor (NGI) on axon growth of chick embryo dorsal root ganglion (DRG). Methods Chick embryo DRG was isolated and cultured, and NGF and NGI were added to observe their effects on axon growth. Results DRG axons grew rapidly in culture medium containing NGF. After adding NGI, this growth was inhibited. Conclusion NGF can promote the growth of DRG axon, while NGI inhibits its growth.