1972年由Glauser提出咳嗽变异性哮喘(cough variantasthma,CVA),这是一种特殊类型的支气管哮喘(简称哮喘),其发病机制和病理生理学表现与典型哮喘相似,但以咳嗽为唯一或主要临床表现,无明显喘息、气促等症状或体征,有呼吸道高反应性。CVA被认为是由嗜酸粒细胞(Eos)、肥大细胞和T细胞等多种炎症细胞参与的慢性、非特异性、变 Glauser, in 1972, presented cough variant asthma (CVA), a specific type of bronchial asthma (asthma) whose pathogenesis and pathophysiology are similar to typical asthma but are unique or predominantly cough Performance, no obvious wheezing, shortness of breath and other symptoms or signs, with respiratory hyperresponsiveness. CVA is thought to be a chronic, nonspecific, variable, and inflammatory cytokine involved in a variety of inflammatory cells such as eosinophils (Eos), mast cells and T cells