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在所试验的37株微生物中,发现刺孢小克银汉霉Cunninghamella echinulata AS 3.3400能在和厚朴酚的8位上进行特异性氧化作用。通过质谱、核磁共振、CD等波谱方法确定了产物(R)-magnolignan C(1)和(S)-magnolignan C(2)的结构。其中1为新化合物。
Of the 37 microorganisms tested, Cunninghamella echinulata AS 3.3400 was found to be able to undergo specific oxidation at position 8 of honokiol. The structures of the products (R) -magnolignan C (1) and (S) -magnolignan C (2) were confirmed by spectroscopic methods such as mass spectrometry, nuclear magnetic resonance, CD and the like. Among them, 1 is a new compound.