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临安天目山制药厂从茶叶中提出鞣质,我们对它进行了抗菌和对离体肠管作用的试验,并以茶叶煎剂进行对照。一、抗菌作用:用平皿内药液稀释法,茶叶鞣质以蒸馏水配成10%(100mg/ml)溶液,茶叶煎剂为100%(1g/ml)溶液。使用金黄色葡萄球菌、宋氏痢疾杆菌、福氏痢疾杆菌、大肠杆菌和绿脓杆菌。结果表明茶叶鞣质和茶叶煎剂对上述5株细菌均有明显的抗菌作用,茶叶鞣质的抗菌效力较茶叶煎剂大3～5倍。二、对大鼠和家兔离体肠管运动的影响:茶叶鞣质12.5～25mg(50ml浴管)对大鼠和家兔离体肠管有轻度抑制作用。药量增加至50～100mg,抑制更加明显,肠管紧张度明显下降,收缩幅度显著变小,甚至完全松弛,收缩停止。换液后恢复正常。茶叶煎剂在相当生药0.25和0.5g(50ml浴管),对大鼠离体肠管表
Lin’an Tianmushan Pharmaceutical Co., Ltd. proposed tannins from tea. We conducted antibacterial and in vitro tests on the intestinal tract, and compared them with tea decoction. First, the antibacterial effect: using the liquid dilution method in the petri dish, the tea tannin is dubbed with distilled water to a 10% (100mg/ml) solution, and the tea decoction is a 100% (1g/ml) solution. Staphylococcus aureus, Shigella sonnei, D. flexneri, E. coli, and P. aeruginosa were used. The results showed that tea tannin and tea decoction all had obvious antibacterial effects on the above five strains of bacteria. The antibacterial effect of tea tannins was 3 to 5 times larger than that of tea decoction. Second, the impact of rat and rabbit isolated intestine movement: tea tannins 12.5 ~ 25mg (50ml bath tube) on rats and rabbits isolated intestinal bowel slightly inhibited. The dose increased to 50 to 100 mg, the inhibition was more pronounced, the bowel tension was significantly decreased, the contraction rate was significantly smaller, or even completely relaxed, and the contraction stopped. Change to normal after changing the liquid. Tea decoction in quite crude drug 0.25 and 0.5g (50ml bath tube), on isolated rat intestine table