美科学家研究口服胰岛素新方法

来源 :现代临床医学生物工程学杂志 | 被引量 : 0次 | 上传用户:chensiyao159
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美国科学家正在试验一种口服胰岛素的新方法,它可望解除糖尿病患者需要不断注射胰岛素之忧.美国珀杜大学的一个科研小组发明的这种方法,是用一种特殊的胶囊包裹着胰岛素.胶囊由两种物质混合组成,其中一种物质可形成大量微孔,另一种物质遇酸时收缩,酸性变弱时又恢复原状,这样制成的胶囊中就含有了大量遇酸关闭的微孔.当这种胰岛素胶囊进入胃里时,在遇到胃酸时胶囊的微孔就关团,因而胰岛素不会泄漏,也就不会受到胃液的破坏;当它进入小肠后,由于环境中酸性减弱,其微孔张大释放出胰岛素,这样胰岛素就可通过小肠进入人体血液循环系统,使糖尿病患者血糖保持正常值.口服胰岛素法最大的障碍是胰岛素进入胃后被胃液破坏.美国科学家的这种新方法在老鼠身上的试验已获得成功,患有糖尿病的老鼠口服胰岛素胶囊后8小时血糖保持正常值. US scientists are experimenting with a new method of oral insulin, which is expected to relieve the need for diabetes in patients with continuous injection of insulin worries.University of Purdue, a research team invented this method is wrapped in a special capsule of insulin. Capsules consist of a mixture of two substances, one of which forms a large number of micropores and the other of which shrinks in the event of acid and restores the original condition when the acidity becomes weak. The capsule thus prepared contains a large amount of micro When this insulin capsule into the stomach, the capsule in the face of acid gastric acid off the pores, so insulin will not leak, it will not be damaged by gastric juice; when it enters the small intestine, due to the acidic environment Weakened, the release of its microporous Zhang insulin, so that insulin can enter the human circulatory system through the small intestine to maintain normal blood glucose in diabetic patients.Oral insulin is the biggest obstacle is the stomach into the stomach after the insulin into the stomach damage.American scientists of this The new method has been successfully tested in mice. Blood glucose remained normal eight hours after oral administration of insulin capsules in diabetic mice.
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