业已证实人类乳癌细胞含有与黄体生成素释放激素(LHRH)和生长抑素(SS)可亲合的受体,两者的拮抗剂可抑制乳癌生长,而其激活剂对人类乳癌的直接影响尚远未得知。本研究应用LHRH和SS的类似物旨在观察其对体外培养的人乳癌细胞的直接作用,并观察此类物质单独或联合应用对乳癌细胞的抑制效应。所用试剂主要有17β-雌二醇、Zoladex、LHRH激活剂D-Trp6、拮抗剂SB_(30)和SB_(75) It has been demonstrated that human breast cancer cells contain receptors that are affinity for LHRH and somatostatin (SS), and antagonists of both can inhibit the growth of breast cancer while the direct effects of its activator on human breast cancer Far from knowing. In this study, LHRH and SS analogues were used to observe the direct effects of LHRH and SS on human breast cancer cells cultured in vitro, and to observe the inhibitory effect of such substances on breast cancer cells, alone or in combination. The main reagents used were 17β-estradiol, Zoladex, LHRH activator D-Trp6, antagonists SB_ (30) and SB_ (75)