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目的 :探讨中心性浆液性脉络膜视网膜病变 (centralserouschorioretinopathy ,CSC)光学相干断层成像 (opticalcoherencetomography ,OCT)的特征和临床应用。方法 :对临床诊断为急性期CSC患者 (即出现主观症状 4～ 8周之内 ) 4 7例 5 0只眼 ,经散瞳后进行OCT检查 ,并对病变图像进行分析和测量。结果 :急性期CSC患者OCT图像特征为累及黄斑中心凹的视网膜神经上皮层的拱形隆起与色素上皮层之间的浆液性弱反射暗区。病变范围 6 18～ 6 40 0 μm ,平均 (3185 0 1± 1495 2 1)μm ;高度 5 9～ 790 μm ,平均 (2 6 2 2 8± 175 2 0 ) μm。经统计学处理 ,表明CSC神经上皮层脱离范围、高度均与视力相关 (P <0 0 5 )。结论 :OCT是一种新型非侵入性的客观定量检查技术。通过OCT对所有急性期CSC眼表现的浆液性视网膜脱离病变的定量分析 ,表明它对CSC的诊断、鉴别诊断、定量测量和病情监测等方面具有重要的临床应用价值
Objective: To investigate the characteristics and clinical application of optical coherence tomography (OCT) in central serouschororetinopathy (CSC). Methods: 477 eyes of 47 CSC patients (4 to 8 weeks after the subjective symptoms were presented) were examined by OCT after mydriasis, and the lesion images were analyzed and measured. RESULTS: OCT images of acute CSC patients were characterized by a serous weakly reflective dark area between the arcuate ridge of the retinal neuroepithelium involving the foveal fovea and the pigment epithelium. The lesions ranged from 6 18 to 6 40 0 μm with an average of (3185 0 1 ± 1495 2 1) μm; height ranged from 59 to 790 μm with an average of (2 6 2 2 8 ± 175 2 0) μm. Statistically, indicating that CSC neuroepithelial detachment range, height and visual acuity (P <0 05). Conclusion: OCT is a new non-invasive and objective quantitative examination technique. Quantitative analysis of serous retinal detachment lesions by OCT in all acute CSC eyes shows that it has important clinical value in the diagnosis, differential diagnosis, quantitative measurement and disease monitoring of CSC