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近期关于胰岛素对造血的影响的研究,方法有二:一是研究缺乏胰岛索(如糖尿病动物模型)时造血情况的变化,从而推测其作用,但这样做除了胰岛素缺乏外,还引起内环境其他因素的改变,如高血糖等,增加实验条件复杂性;另一方法是加入外源性胰岛素之后观察其作用。如果加入动物体内也会引起血糖降低等改变不利于判断。将胰岛索加在体外培养体系中或体内扩散盒内,则条件易于控制。本文讨论用不同方法得的结果。 P0ljak-Blazi等在1980年报道;采用静脉注射四氧嘧啶制备糖尿病小鼠模型,按病程长短不同分别作骨髓细
There are two ways to study the effect of insulin on hematopoiesis. One is to study the changes of hematopoiesis in the absence of pancreatic islets (such as diabetic animal models), so as to speculate on its role. However, in addition to the lack of insulin, it also causes other internal environment Changes in factors, such as hyperglycemia, increase the complexity of the experimental conditions; the other method is to observe the role of exogenous insulin. If you join the animal body will cause blood sugar and other changes are not conducive to judge. Soy islets in vitro culture system or diffusion box, the conditions are easy to control. This article discusses the results obtained by different methods. P0ljak-Blazi et al reported in 1980; alloxan prepared by intravenous injection of diabetic mouse model, according to the length of the course of different bone marrow fine