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前言早在1920年人们已发现正常动物组织中含有镍,随后又发现了镍的一系列的生物学作用,但镍作为动物营养不可缺少的微量元素之一是在1970年,Nielsen等首次用缺镍的饲料喂养动物后,才得到直接证实。镍能作用于生物系统,镍的生理功能可能包括激素,细胞膜和脂质的代谢,已知正常人体组织中也含有一定量的镍,血液中镍浓度常维持在一个特定的范围内。在某些病理状态下有明显的改变,如急性心肌梗塞、烧伤、中风发作时血清中镍浓度升高,慢性尿毒症、肝硬化患者血清中镍浓度下降等。
Preface As early as 1920 people have found that the normal animal tissue contains nickel, and later found a series of biological effects of nickel, but nickel is indispensable for animal nutrition, one of the trace elements in 1970, Nielsen and other first missing Nickel feed after feeding animals, was directly confirmed. Nickel can act on biological systems. The physiological functions of nickel may include the metabolism of hormones, cell membranes and lipids. It is known that normal human tissues also contain a certain amount of nickel, and the nickel concentration in the blood is often maintained within a specific range. In some pathological conditions have been significantly changed, such as acute myocardial infarction, burns, increased serum nickel concentration in stroke onset, chronic uremia, serum nickel in patients with cirrhosis decreased.