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药物代谢动力学(pharmacokinetics,药动学)一词,源于1937年Theorell的一篇权威性文章。1961年,Nelson发表了第一篇药动学原理的英文综述。药动学系研究药物在机体的吸收、分布、代谢和排泄的时间过程。有些作者把它扩展到包括上述许多过程与药物的治疗作用和不良反应的强度和时间的关系。要注意药动学与药效学的区别。药效学(pharmacodynamics)系研究药物对机体的作用,而药动学则研究机体对药物的作用的速率过程。理论上,药效学是研究药物效应与其在组织
The term pharmacokinetics derives from an authoritative article by Theorell in 1937. In 1961, Nelson published the first English summary of the pharmacokinetic principle. Pharmacokinetics Department of drug absorption in the body, distribution, metabolism and excretion of time course. Some authors have extended it to include many of the above-mentioned processes and drug treatment and the relationship between the intensity and time of adverse reactions. Pay attention to the difference between pharmacokinetics and pharmacodynamics. Pharmacodynamics studies the effects of drugs on the body, while pharmacokinetics study the rate of the body’s action on drugs. In theory, pharmacodynamics is the study of drug effects and its effects on the organization