论文部分内容阅读
Spl/Kruppel样转录因子(Spl-like and Kruppel-like tran- scription factors,Spl/KLFs)是参与真核细胞转录的高度相关锌指蛋白,以细胞和启动子特异性方式通过调控富含GC启动子的基因表达,参与调节细胞功能如细胞增生、凋亡、分化和肿瘤形成.
Spl-like and Kruppel-like trancription factors (Spl / KLFs) are highly involved zinc finger proteins that are involved in the transcription of eukaryotic cells in a cellular and promoter-specific manner by regulating GC-rich Gene expression in the subfamily is involved in the regulation of cell functions such as cell proliferation, apoptosis, differentiation and tumorigenesis.