本文报道雷公藤对感染日本血吸虫小白鼠肝虫卵肉芽肿的影响。结果显示实验组肝单卵和多卵肉芽肿直径均明显小于对照组:肉茅肿内浆细胞和嗜酸性粒细胞极为罕见;平均每对成虫排入肝内的虫卵数少于对照组。表明雷公藤对日本血吸虫病鼠肝虫卵肉芽肿的形成有明显抑制作用。 This paper reports the effects of Tripterygium wilfordii on the granulomatosis of liver worms infected with Schistosoma japonicum in mice. The results showed that the diameters of single egg and multiple egg granuloma in the experimental group were significantly smaller than those in the control group: Plasma cells and eosinophils were extremely rare in the rumorgrass; the average number of eggs per pair of adults discharged into the liver was less than the control group. It was shown that Tripterygium wilfordii can obviously inhibit the formation of granuloma of liver schistosomiasis mice.