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曾有报导,宫内感染鼠弓形体、巨细胞病毒及疱疹病毒,无论在实验动物还是在人,皆同时抑制体液和细胞免疫反应,导致胎儿生长迟滞、胚胎病、中枢神经受累和免疫异常。有些宫内感染后,在出生时没有症状,其感染后果可能在生后数月乃至数年才表现出来。本文作者检查了2029例在医院出生的婴儿,筛选出48例具有高血清IgM婴儿,应用RID研究了其血液IgM、IgA及IgG的含量变化,以及淋巴细胞功能等项免疫指标。
It has been reported that intrauterine infection of toxoplasma gonorrhoeae, cytomegalovirus and herpes virus, both in experimental animals and in humans, inhibit both humoral and cellular immune responses, resulting in fetal growth retardation, embryonal disease, central nervous involvement and immune abnormalities. Some intrauterine infection, no symptoms at birth, the consequences of infection may be shown months or even years after birth. The authors examined 2029 infants born in the hospital and screened 48 infants with high serum IgM. RID was used to study the changes of blood IgM, IgA and IgG levels, as well as immune indicators such as lymphocyte function.