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雾化吸入吗啡可增进活动耐力,并可缓解慢性肺疾患或肺癌病人的呼吸困难,作者报道1例病人作吗啡雾化吸入发生了急性呼吸抑制。此例系74岁高血压妇女,每天服用依那普利5mg和阿替洛尔50mg,因腰痛、食欲不振、体重下降入院诊治,经摄胸片发现右上肺有晚期转移病灶,又经CT和TC99M骨扫描证实脊柱(颈椎6～7、胸1～2、胸8～11和腰椎1～3)有多处癌转移,第1～6肋侧面也有转移灶。诊断为肺癌并发骨转移。因疼痛严重用缓释型吗啡口服每3h 10mg,有时需加用普通吗啡
Inhalation of morphine by inhalation enhances activity tolerance and can alleviate the difficulty of breathing in patients with chronic lung disease or lung cancer. The authors reported that one patient had acute respiratory depression with morphine aerosolized inhalation. This case was a 74-year-old hypertensive woman who took enalapril 5mg and atenolol 50mg daily. She was admitted to hospital because of low back pain, poor appetite, and weight loss. She had chest radiographs and found that there were advanced metastatic lesions in the right upper lung, and CT and TC99M bone scan confirmed that the spine (6 to 7 in the cervical spine, 1 to 2 in the thoracic cavity, 8 to 11 in the thoracic cavity, and 1 to 3 in the lumbar spine) had multiple cancer metastasis, and metastatic lesions were also found on the side of the first to sixth ribs. Diagnosis of lung cancer with bone metastases. For severe pain, use sustained-release morphine orally every 3h 10mg, sometimes add regular morphine