活性组分和赋形剂的相容性连同其他因素决定着配方的稳定性。赋形剂在各个方面影响药物固态的稳定性,可出现药物和赋形剂间的直接化学反应或由吸附潮气和催化作用引起的间接化学反应。某些相互作用能改变成品的生物有效性或稳定性。因此需选择能作出快速和可靠的可能相互作用信息的方法来评价固态的 The compatibility of the active ingredient with the excipient, among other factors, determines the stability of the formulation. Excipients affect the stability of the drug solid in all aspects, and direct chemical reactions between the drug and the excipient or indirect chemical reactions caused by adsorption moisture and catalysis can occur. Certain interactions can alter the bioavailability or stability of the finished product. Therefore, we must choose to make fast and reliable possible interaction of information to evaluate the solid state