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本文研究目的是检验结合临床资料可否提高口腔上皮异常增生组织病理学诊断的准确性及一致性。 研究设计 6名有执照的口腔颌面部病理学家结合提供的临床资料对120例口腔活检标本(其范围从上皮单纯增生到严重异常增生)进行病理学诊断,结果与标准诊断进行比较.以前他们都曾经对这些切片作过诊断,为了避免受以前印象的干扰,保证前后诊断的时间间隔一年以上。 结果与讨论 这批结合临床资料的病理学诊断与标准诊断的精确符合率为38.5％;组织学分级的相符率为85.4％;上皮异常增生鉴别诊断的相符率为71.4％。将提供临床资料前后的病理学诊断进行比较
The purpose of this study is to examine whether the combination of clinical data can improve the accuracy and consistency of histopathological diagnosis of oral epithelial dysplasia. Study Design Six licensed oral and maxillofacial pathologists performed a pathologic diagnosis of 120 oral biopsies (ranging from simple hyperplasia of the epithelium to severe dysplasia) in combination with available clinical data and compared with standard diagnoses. All of them have previously diagnosed these slices, in order to avoid interference with the previous impression, to ensure that more than one year before and after the diagnosis. RESULTS AND DISCUSSION The exact coincidence rate of pathological diagnosis and standard diagnosis combined with clinical data was 38.5%. The coincidence rate of histological grading was 85.4%. The coincidence rate of differential diagnosis of epithelial dysplasia was 71.4%. Will provide clinical data before and after the pathological diagnosis for comparison