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目的研究分析腹腔镜子宫腺肌症病灶切除术后联合促性腺激素释放激素激动剂(GnRH-a)对于子宫腺肌症的临床疗效。方法选取2013年1月—2014年1月本院收治的70例子宫腺肌症患者为研究对象,随机分成观察组和对照组各35例,对照组患者给予腹腔镜子宫腺肌症病灶切除术治疗,观察组在对照组治疗后联合应用GnRH-a 3个月,观察两组患者治疗方式的临床疗效。结果观察组患者较对照组失访率低,差异具有统计学意义(P<0.05)。用药结束后,观察组患者痛经程度、月经量、复发率、子宫体积均较对照组有显著改善,差异均具有统计学意义(P<0.05)。结论腹腔镜子宫腺肌症病灶切除术后联合促性腺激素释放激素激动剂治疗,不但能巩固临床疗效,而且能增加患者的依从性,降低失访率,减少复发,是当前治疗子宫腺肌症较理想的方案,值得临床推广应用。
Objective To study the clinical effect of GnRH-a combined with gonadotropin-releasing hormone agonist (GnRH-a) on adenomyosis after laparoscopic resection of adenomyosis. Methods Seventy patients with adenomyosis admitted to our hospital from January 2013 to January 2014 were selected and randomly divided into observation group (35 cases) and control group (35 cases). Patients in the control group were given laparoscopic adenomyosis The treatment group and the observation group were given GnRH-a for 3 months after the treatment in the control group, and the clinical curative effect of the two groups was observed. Results The observation group had a lower rate of follow-up than the control group, with significant difference (P <0.05). After treatment, the degree of dysmenorrhea, menstrual flow, recurrence rate and uterine volume in the observation group were significantly improved compared with those in the control group, with statistical significance (P <0.05). Conclusion Laparoscopic adenomyosis after focal resection combined with gonadotropin-releasing hormone agonist therapy not only consolidate the clinical efficacy, but also increase patient compliance, reduce the rate of loss of follow-up, reduce recurrence, is the current treatment of adenomyosis The ideal solution is worthy of clinical application.