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目的:观察益气健脾方结合ω-3脂肪酸在结肠肿瘤患者围手术期营养支持治疗中的作用。方法:将临床诊断为结肠肿瘤并接受静脉营养支持的120例术后患者按其意愿分为治疗组65例和对照组55例,对照组采用全营养混合液加20%丙氨酰谷氨酰胺行营养支持治疗,治疗组在对照组的基础上加用10%ω-3鱼油脂肪乳注射液与益气健脾方行营养支持治疗。观察比较两组术前及术后第1、3、7天淋巴细胞数、术后并发症、术后转归、术后住院天数和住院总费用。结果:治疗组在提高患者术后淋巴细胞数、减少术后并发症及术后转归等方面均明显优于对照组(P<0.05);两组术后住院天数及住院总费用比较,差异无统计学意义(P>0.05)。结论:益气健脾方结合ω-3脂肪酸能有效提高结肠肿瘤围手术期患者的免疫力,减少术后并发症的发生,促进患者术后肠道功能恢复,值得进一步研究和推广。
Objective: To observe the role of Yiqi Jianpi Decoction combined with omega-3 fatty acids in perioperative nutritional support in patients with colon cancer. Methods: 120 patients with clinically diagnosed colonic tumors and intravenous nutritional support were divided into treatment group (n = 65) and control group (n = 55) according to their wishes. The control group was treated with total nutrient solution plus 20% alanylglutamine Nutritional support treatment line, the treatment group in the control group based on the use of 10% omega-3 fish oil emulsion injection and nourishing qi spleen nutrition support treatment. The number of lymphocytes, postoperative complications, postoperative outcome, postoperative hospital stay and total cost of hospitalization were observed and compared before and after operation. Results: The treatment group was significantly better than the control group in improving postoperative lymphocyte count, reducing postoperative complications and prognosis (P <0.05). The difference between the two groups in the number of hospitalization days and the total cost of hospitalization was significant No statistical significance (P> 0.05). Conclusion: The combination of Yiqi Jianpi prescription and omega-3 fatty acids can effectively improve the perioperative immunity of patients with colon cancer, reduce postoperative complications and promote the recovery of intestinal function after operation, which deserves further study and promotion.