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目的:分析磁共振波谱在胶质瘤和脑膜瘤中的诊断和鉴别诊断价值。材料和方法:29例患者(胶质瘤16例,脑膜瘤13例)先完成常规平扫,后均行PRESS序列行单体素波谱检查,部分同时进行STEAM序列检查。结果:胶质瘤组的病灶侧和对侧的NAA/Cr之间有显著性差异(P<0.01),病灶侧Cho/Cr以及Cho/Creontra和对侧Cho/Cr之间有差异(P<0.05);mI/Crcontra在高度恶性和低度恶性胶质瘤之间有差异(P<0.05)。脑膜瘤组的波谱在1.4×10-6～1.6×10-6处可见倒置的Ala双峰,良性和恶性脑膜瘤的Cho/Crcontra比较有差异(P<0.05);NAA/Cr在恶性脑膜瘤瘤周1cm处的水肿区与对侧比较有差异。结论:mI/Cr可以作为低度和高度恶性胶质瘤的分级指标,Lip可能在胶质瘤的分级中有意义。Ala可以作为脑膜瘤的诊断标志,Cho/Crcontra在脑膜瘤的良、恶性分级中有意义。
Objective: To analyze the diagnostic value of magnetic resonance spectroscopy in glioma and meningioma. MATERIALS AND METHODS: Twenty-nine patients (16 gliomas and 13 meningeomas) underwent conventional plain radiography. PRESS sequence was followed by single elemental spectroscopy, and some of them were simultaneously examined by STEAM. Results: There was a significant difference (P <0.01) between NAA / Cr in lesion side and contralateral side of glioma group and between Cho / Cr and Cho / Creontra in lesion side and contralateral Cho / Cr group (P < 0.05). The difference of mI / Crcontra between high grade and low grade glioma (P <0.05). The spectrum of meningioma showed an inverted Ala peak at 1.4 × 10-6 ~ 1.6 × 10-6, Cho / Crcontra was significantly different between benign and malignant meningiomas (P <0.05), while NAA / Cr in malignant meningiomas Peritumor at 1cm at the edema area and contralateral differences. Conclusion: mI / Cr can be used as a grading index for low grade and high grade gliomas, and Lip may be of significance in the classification of gliomas. Ala can be used as a diagnostic marker of meningioma, Cho / Crcontra meaningful in meningioma benign and malignant grading.