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目的：观察四生汤减轻肝动脉化疗栓塞术（ＴＡＥ）毒副反应的临床疗效。方法：将５４例行ＴＡＥ术的肝癌患者分为四生汤组（３４例）与对照组（２０例），将两组ＴＡＥ术后主要临床症状变化和术前及术后２周的外周血象及部分细胞免疫功能进行比较。结果：四生汤组在改善消化道反应方面明显优于对照组（Ｐ＜０．０５），在外周血白细胞及细胞免疫功能（ＮＫ细胞及ＬＡＫ细胞活性）方面，对照组在ＴＡＥ术后呈明显下降，而四生汤组虽略有下降，但与术前比较无显著性差异。结论：四生汤既能改善ＴＡＥ术者的临床主要症状，又能显著地提高患者的外周血白细胞和细胞免疫功能。
OBJECTIVE: To observe the clinical efficacy of Sisheng decoction in reducing the toxicity of hepatic arterial chemoembolization (TAE). METHODS: 54 cases of liver cancer patients undergoing TAE were divided into Sisheng Decoction group (34 cases) and control group (20 cases). The main clinical symptoms of the two groups after TAE change and preoperative and postoperative 2 weeks of peripheral blood And some of the cellular immune functions were compared. Results: The Sisheng Decoction group was superior to the control group in improving the digestive tract reaction (P<0.05). In the peripheral blood leukocyte and cellular immune function (NK cell and LAK cell activity), the control group was presented after TAE. Significantly decreased, while the four raw soup group decreased slightly, but no significant difference compared with preoperative. Conclusion: Sisheng Decoction can not only improve the clinical symptoms of TAE patients, but also can significantly improve the patients’ peripheral blood leukocyte and cellular immune function.