弥漫性泛细支气管炎(DPB)主要病变在呼吸细支气管,弥漫于两肺,是造成严重呼吸障碍的疾病,工藤翔二发现80%以上的DPB合并有慢性副鼻窦炎,为难治性呼吸道感染症,预后不良,并出现冷凝集效价增高等免疫学异常。本病在日本多见,但在欧美国家几乎看不到,这与只有蒙古人种才带有的HLA-BW54抗原有密切关系。其主要症状为咳嗽、喀痰和活动时气短。体检时,多可闻及两肺水 Diffuse bronchiolitis (DPB) the main lesion in the respiratory bronchioles, diffuse in both lungs, is a serious respiratory disorder caused by disease, Kudou Shinji found that more than 80% of DPB with chronic sinusitis, refractory respiratory tract infections Symptoms, poor prognosis, and condensation set agglutination increased immunological abnormalities. The disease is more common in Japan, but almost invisible in Europe and the United States, which is only closely linked with the HLA-BW54 antigen that Mongolian people have. The main symptoms are cough, phlegm and shortness of breath during activities. Physical examination, more than two lungs and water can be heard