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目的探讨安庆农村社区45～75岁原发性高血压人群血脂与年龄、性别的关系,为从多重因素控制心脑血管疾病的防治提供科学依据。方法采用流行病学现况调查方法 ,用整群抽样抽取安庆农村社区45～75岁原发性高血压患者进行问卷调查和体格检查,采用全自动生化分析酶法检测总胆固醇(TC)、甘油三酯(TG)和高密度脂蛋白(HDL-C)3个指标水平。结果纳入分析对象共8562人,女性的TC和TG平均水平均高于男性,但HDL-C平均水平低于男性,差异均具有统计学意义(P<0.001)。女性的高TC和高TG患病率均高于男性(P<0.001)。以年龄每5岁分为一组,男性血脂水平主要表现为TG和TC水平均随着年龄的增加而降低,女性结果相反。在校正相关变量后的线性回归结果显示,男性每增加5岁,TG和TC分别下降0.04mmol/L和0.02mmol/L(P<0.05),以45～50岁组为参照组,各年龄组与其比较的TG水平差异均具有统计学意义(P<0.001);女性每增加5岁,TG和TC就分别增加0.02mmol/L和0.05mmol/L,差异均具有统计学意义(P<0.05)。多变量Logis-tic回归校正相关变量后的分析结果发现,男性每增加5岁,患高TG和高TC的发作风险分别下降24%(OR=0.76,95%CI:0.68～0.85)和13%(OR=0.87,95%CI:0.77～0.98)。结论安庆农村社区45～75岁高血压人群的TC和TG水平普遍较低;不同性别间的血脂水平是有差异的。该人群高TC、高TG以及低HDL-C的患病率相对较低,这与农村地区该类人群大部分还在从事适宜体力活动、多吃蔬菜水果以及低脂饮食有关。
Objective To investigate the relationship between serum lipids and age and gender in 45-75-year-old population with hypertension in rural communities in Anqing, and to provide a scientific basis for the prevention and treatment of cardiovascular and cerebrovascular diseases by multiple factors. Methods A questionnaire survey and physical examination of 45-75 years-old patients with essential hypertension in rural community of Anqing were conducted by cluster sampling method using the method of epidemiological survey. Total cholesterol (TC), glycerol Triglyceride (TG) and high-density lipoprotein (HDL-C) three indicators. Results A total of 8562 subjects were enrolled in this study. The average levels of TC and TG in women were higher than those in men, but the average HDL-C levels were lower than those in men (P <0.001). Women with high TC and high TG prevalence were higher than men (P <0.001). Divided into groups of 5-year-old age, male blood lipid levels mainly as the TG and TC levels are lower with increasing age, the opposite results for women. Linear regression after adjusting for related variables showed that for each 5-year increase in men, TG and TC decreased by 0.04 mmol / L and 0.02 mmol / L, respectively (P <0.05) (P <0.001). For each 5-year-old female, TG and TC increased by 0.02 mmol / L and 0.05 mmol / L respectively, the difference was statistically significant (P <0.05) . Multivariate Logis-tic regression analysis of correlation variables found that for each 5-year increase in men with high TG and high TC seizure risk decreased by 24% (OR = 0.76, 95% CI: 0.68 to 0.85) and 13% (OR = 0.87, 95% CI: 0.77-0.98). Conclusion The levels of TC and TG in the 45 ~ 75-year-old hypertensive population in rural areas of Anqing are generally low. There are differences in blood lipid levels among different sexes. The prevalence of high TC, high TG and low HDL-C in this population is relatively low, which is related to the fact that most of these people in rural areas are still engaged in physical activity, eating more fruits and vegetables and eating low-fat foods.