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目的回顾分析住院患者梅毒螺旋体抗体及相关传染性标志物检测结果,为梅毒的防治提供依据和意见。方法选取2014年1月至12月永嘉县人民医院11 862名住院患者,进行抗梅毒螺旋体(TP)抗体、乙型肝炎病毒表面抗原(HBsAg)、抗丙型肝炎病毒(HCV)抗体和抗人类免疫缺陷病毒(HIV)抗体检测。按照不同性别、年龄段、科室和疾病类型进行抗TP抗体阳性率、HBsA g阳性率、抗HCV抗体阳性率、抗HIV抗体阳性率的比较。结果抗TP抗体确诊阳性246例,阳性率2.07%,男性阳性率为2.34%,女性阳性率为1.80%,男女性别差异具有统计学意义(χ~2=4.401,P=0.036)。抗TP抗体阳性率在31~45岁组最高,为2.51%,科室方面,骨科最高,为3.25%,产科最低,为0.94%。内科、外科、骨科患者不同疾病间阳性率不同。246例梅毒抗体阳性患者中,HBsAg阳性31例(占11.79%)、抗HCV抗体阳性4例(占1.63%)、抗HIV抗体阳性1例(占0.41%)。结论该院住院患者梅毒抗体阳性率具有性别、年龄和科室病种差异,且阳性者合并高HBsA g和抗HCV抗体阳性率,须加强监测和护理,防止院内传播及患者间交叉感染。
Objective To retrospectively analyze the detection results of syphilis antibodies and related infectious markers in hospitalized patients and provide evidences and suggestions for the prevention and treatment of syphilis. Methods A total of 11 862 hospitalized patients in Yongjia People’s Hospital from January 2014 to December 2014 were enrolled in this study. The anti-Treponema pallidum (TP) antibody, HBsAg, anti-HCV antibody and anti-human Immunodeficiency virus (HIV) antibody test. The anti-TP antibody positive rate, HBsA g positive rate, anti-HCV antibody positive rate and anti-HIV antibody positive rate were compared according to different genders, age groups, departments and types of diseases. Results There were 246 positive cases diagnosed with anti-TP antibody, the positive rate was 2.07%. The positive rate was 2.34% in male and 1.80% in female. The sex difference was statistically significant (χ ~ 2 = 4.401, P = 0.036). The positive rate of anti-TP antibody in the 31-45 age group was the highest (2.51%). In the department, the highest orthopedic rate was 3.25% and the obstetric was the lowest, 0.94%. Internal medicine, surgery, orthopedic patients with different positive rates of different diseases. Of the 246 syphilis positive patients, 31 were HBsAg positive (11.79%), 4 were anti-HCV (1.63%) and 1 was anti-HIV antibody (0.41%). Conclusions The prevalence of syphilis antibody in inpatients in this hospital is different from sex, age and departmental diseases. Positive patients with high HBsAg and anti-HCV antibody positive rates should be monitored and nursed back to prevent in-hospital transmission and cross-infection among patients.