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目的：探讨动态检测血清降钙素在指导下呼吸道感染抗生素治疗中的临床价值。方法：选取我院 2013 年 3 月耀2014 年 3 月行下呼吸道感染抗生素治疗患者 100 例，依据使用抗生素的最终临床指标将患者分为 A 组（对抗生素治疗有效）和 B 组（对抗生素治疗无效），每组 50 例。观察两组确诊感染后不同时间的血清 PCT 水平和炎症指标。结果：A 组感染可能性评分（IPS）、中性粒细胞分类计数（N）、白细胞计数（WBC）、超敏 c-反应蛋白检测（hs-CRP）、体温与 B 组比较，无显著差异（P跃0.05），无统计学意义；A 组的血清 PCT 水平从第一天到第七天逐渐下降，差异显著（P约0.05），具有统计学意义；B 组的血清 PCT 水平从第一天到第七天逐渐上升，差异显著（P约0.05），具有统计学意义；第一天，A 组的血清 PCT 水平与 B 组比较，无显著差异（P跃0.05），无统计学意义；A 组第三天、第五天、第七天的血清 PCT 水平与 B 组比较，差异显著（P约0.05），具有统计学意义。结论：PCT 检测可有效反映患者使用抗生素的疗效，从而减少耐药菌。
Objective: To investigate the clinical value of dynamic detection of serum calcitonin in the antibiotic therapy of lower respiratory tract infection. Methods: A total of 100 patients undergoing antibiotic treatment of lower respiratory tract infection in our hospital from March 2013 to March 2014 were enrolled. Patients were divided into group A (effective for antibiotic treatment) and group B (antibiotic treatment) according to the final clinical criteria of using antibiotics Invalid), 50 cases in each group. Serum PCT levels and inflammatory markers were observed at different times after the two groups were diagnosed. Results: There was no significant difference in the infection possibility score (IPS), neutrophil count (N), white blood cell count (WBC), hs-CRP, (P <0.05). There was no significant difference between the two groups (P> 0.05). The level of PCT in group A decreased gradually from the first day to the seventh day There was a significant difference between the first day and the seventh day (P> 0.05). There was no significant difference in serum PCT level between the two groups (P> 0.05) The serum PCT level of the third day, the fifth day and the seventh day in group A was significantly different from that in group B (P about 0.05), which was statistically significant. Conclusion: PCT test can effectively reflect the efficacy of antibiotics in patients, thereby reducing drug-resistant bacteria.