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目的 :探讨不明原因反复自然流产 (RSA)患者在不同时期血清sIL - 2R水平。方法 :采用双抗体夹心ELISA法测定了 2 6例非孕期RSA患者 ,2 2例孕期RSA患者 ,8例出现先兆流产的孕期RSA患者 ,2 0例正常妊娠的孕妇与2 1例正常经产妇血清中sIL - 2R水平。结果 :出现先兆流产组血清sIL - 2R水平显著高于其它组 (P <0 .0 1) ,其余 4组间无显著性差异 (P >0 .0 5 )。结论 :血清sIL - 2R水平升高与先兆流产有关 ,RSA患者孕期血清sIL - 2R水平升高应警惕再次发生流产的可能。
Objective: To investigate the serum levels of sIL - 2R in patients with unexplained recurrent spontaneous abortion (RSA) at different stages. METHODS: Twenty-six non-pregnant RSA patients, 22 RSA patients during pregnancy, 8 pregnant women with RSA during pregnancy induced by threatened abortion, 20 pregnant women with normal pregnancy and 21 normal pregnant women with serum SIL-2R levels. Results: Serum levels of sIL - 2R in patients with threatened abortion were significantly higher than those in other groups (P <0.01). There was no significant difference between the other 4 groups (P> 0.05). Conclusion: Elevated serum levels of sIL - 2R are associated with threatened abortion. The increase of sIL - 2R level in serum of RSA patients should be alert to the possibility of miscarriage again.