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目的 提出并详细描述一种对帕金森病 (PD)患者运动功能障碍的临床评分。方法 运用统计学方法对这一评分量表的一致性和敏感性进行检验 ,对 2 0例PD患者的帕金森病运动功能评分量表 (MDR SPD)评分结果做Kappa检验 ,对 2 0例PD患者治疗前后的评分结果进行t检验。 结果 该量表 16个项目的Kappa检验 ,最低K =0 .6 6 ,最高K =0 .97;t检验示治疗前后评分结果差异有显著性 (P <0 .0 1)。结论 MDRSPD可重复性较好 ,且能敏感地反映出病情变化 ,是一种使用方便的、较为精确和稳定的量表化方法 ,可用于PD患者的病情严重程度和治疗疗效的评定。
Objective To propose and describe in detail a clinical score for motor dysfunction in patients with Parkinson’s disease (PD). Methods The consistency and sensitivity of this rating scale were tested by statistical methods. Kappa test was used to evaluate the Parkinson’s Disease Motor Function Rating Scale (MDR SPD) score of 20 PD patients. Twenty patients with PD Patient scores before and after treatment t test. Results The Kappa test of 16 items in this scale showed that the lowest K was 0.666 and the highest K was 0.97. The t test showed that there was a significant difference between before and after treatment (P <0.01). Conclusions The reproducibility of MDRSPD is good, and it can reflect the change of disease sensitively. It is a convenient, accurate and stable scale method and can be used to evaluate the severity of disease and curative effect of PD patients.