肺癌是最常见的恶性肿瘤,因为早期发现困难,所以就诊时大多已经属于中晚期,以化疗为主的全身治疗是失去手术机会的晚期非小细胞肺癌患者的标准一线治疗,含铂的第三代化疗方案能使部分患者得到缓解,且可延长生存期、改善生活质量,但其有效率仅30%左右。目前因为缺乏预测临床疗效 Lung cancer is the most common malignancy. Because of the early detection difficulties, most of the patients are already in advanced stages of treatment. Chemotherapy-based systemic therapy is the standard first-line treatment for patients with advanced non-small cell lung cancer who have lost their chance of surgery. On behalf of the chemotherapy regimen can make some patients be relieved, and can extend the survival and improve the quality of life, but its efficiency is only about 30%. Because of the lack of prediction of clinical efficacy