一、多发性硬化(MS)和实验性自身免疫性脑脊髓炎多发性硬化是中枢神经系统(CNS)白质炎症脱髓鞘性自身免疫性疾病,临床主要表现为缓解复发和阶梯进展的视力、运动和平衡障碍。MS按疾病的病程分为以下几种类型:缓解复发型、原发进展和继发进展型。MS病情的进展是髓鞘抗原特异性T细胞,以髓鞘为靶,导致CNS的炎症浸润,最后导 First, multiple sclerosis (MS) and experimental autoimmune encephalomyelitis Multiple sclerosis is a central nervous system (CNS) white matter inflammatory demyelinating autoimmune disease, the clinical manifestations of mitigation of recurrence and staircase progressive vision, Movement and balance disorders. MS according to the disease course is divided into the following types: ease recurrence, primary progress and secondary progress. The progression of MS is myelin antigen-specific T cells, targeting myelin, leading to inflammatory infiltration of the CNS and finally to